Technology

Building Eye Innovation
technology

A Revolution in Ophthalmological Treatments

MgShell aspires to inspire a change in ophthalmology. We have developed a magnesium-based drug delivery platform capable of reshaping patient care, enhancing treatment adherence for patients suffering from retinal diseases, and lowering healthcare expenses.

Our platform is currently undergoing pre-clinical validation with active principles used for the treatment of the exudative form of age-related macular degeneration and diabetic macular edema. We have demonstrated biological and pharmacological compatibilities and achieved miniaturization for intravitreal injection procedures.

Patents

Device for intraocular release of a medicament
  • Device configurations, type of drug release, method for the production of an intraocular device.
  • Patent granted in Italy (2019), Europe (2023) and Japan (2023), pending in USA and others.
Controlled release device
  • Further device configurations, method for manufacturing, filling and closing, different uses in the human body.
  • Patent granted in Italy (2021), pending in USA, Europe, Japan and others.

Publications

Investigating flow-induced corrosion of magnesium in ophthalmological milieu
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A cutting force and hole geometry study for precision deep-hole microdrilling of magnesium
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Cold microdrawing of pure magnesium capillary structures for biomedical applications
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A deep-hole microdrilling study of pure magnesium for biomedical applications
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Evaluation of the ocular fluid dynamic effects on intraocular magnesium-based device: A comparison between CFD and FSI approaches
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A drug delivery analysis of large molecules in ocular vitreous chamber: Dependency on saccadic movements after intravitreal injection
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A combined approach for the analysis of ocular fluid dynamics in the presence of saccadic movements
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Saccadic movement effects on intraocular drug delivery for a wet-AMD clinical case
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Why Magnesium

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Headquarters

MGSHELL SRL
Via G. Durando, 39
20158 Milan – Italy

Registered office

Viale Romagna, 59
20133 Milan – Italy

VAT ID –  IT10767230963

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